Phenylacetyl-Coenzyme A (sodium salt)

TargetMol
Product Code: TAR-T37755
Supplier: TargetMol
CodeSizePrice
TAR-T37755-1mg1mg£261.00
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Quantity:
TAR-T37755-5mg5mg£938.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Further Information

Bioactivity:
Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such asPseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.1It is a precursor in the synthesis of the antibiotic penicillin G found in industrial strains ofP. chrysogenum. Phenylacetyl-CoA also acts as an effector molecule of the TetR family transcriptional repressor PaaR inT. thermophilusand the GntR family transcriptional regulator PaaX inE. coliandPseudomonas, binding to each protein to induce derepression of various genes.2
CAS:
0
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Sakamoto, K., Agari, Y., Kuramitsu, S., et al.Phenylacetyl coenzyme A is an effector molecule of the TetR family transcriptional repressor PaaR from Thermus thermophilus HB8J. Bacteriol.193(17)4388-4395(2011) Mi?ambres, B., Mart?nex-Blanco, H., Olivera, E.R., et al.Molecular cloning and expression in different microbes of the DNA encoding Pseudomonas putida U phenylacetyl-CoA ligase. Use of this gene to improve the rate of benzylpenicillin biosynthesis in Penicillium chrysogenumJ. Biol. Chem.271(52)33531-33538(1996)