TargetMol

Crocin II

Product Code:
 
TAR-T3779
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3779-1mg1mg£106.00
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TAR-T3779-5mg5mg£148.00
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TAR-T3779-10mg10mg£203.00
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TAR-T3779-25mg25mg£327.00
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TAR-T3779-50mg50mg£455.00
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TAR-T3779-100mg100mg£623.00
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TAR-T3779-500mg500mg£1,211.00
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Further Information

Bioactivity:
Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, crocetin, can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.
CAS:
55750-84-0
Formula:
C38H54O19
Molecular Weight:
814.831
Pathway:
Immunology/Inflammation; Apoptosis; Proteases/Proteasome; Neuroscience
Purity:
0.9919
SMILES:
CC(C=CC=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=C/C=C/C=C(C)/C=C/C=C(C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H](O)[C@H]1O
Target:
Caspase; COX; NO Synthase

References

Lee IA,et al. Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite Crocetin. Biol Pharm Bull. 2005 Nov;28(11):2106-10.