15-keto Prostaglandin F2 α
| Code | Size | Price |
|---|
| TAR-T37991-1mg | 1mg | £294.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T37991-5mg | 5mg | £1,057.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T37991-10mg | 10mg | £1,820.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
15-keto Prostaglandin F2α (15-keto PGF2α) is the first metabolite of PGF2α. in the 15-hydroxy PGDH pathway. It is one of the critical components in the goldfish and Atlantic salmon postovulatory pheromone. [1] [2] 15-keto PGF2α stimulates the male goldfish and salmon olfactory receptors with detection thresholds of 10-12 and 10-8 M, respectively. [1] [2] 15-keto PGF2α is 10-fold less active than PGF2α in decreasing rabbit intraocular pressure.[3]
CAS:
35850-13-6
Formula:
C20H32O5
Molecular Weight:
352.471
Pathway:
GPCR/G Protein|Metabolism|Immunology/Inflammation
Purity:
0.98
SMILES:
CCCCCC(=O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C/CCCC(O)=O
Target:
Prostaglandin Receptor|Endogenous Metabolite
References
Sorensen PW, et al. F prostaglandins function as potent olfactory stimulants that comprise the postovulatory female sex pheromone in goldfish. Biol. Reprod. 39(5), 1039-1050 (1988).
Moore A, et al. Electrophysiological and endocrinological evidence that F-series prostaglandins function as priming pheromones in mature male Atlantic salmon (Salmo salar) PARR. J Exp Biol. 199(Pt 10), 2307-2316 (1996).
Woodward DF, et al. Marked differential effects of prostanoid metabolites on rabbit intraocular pressure. Ophthalmic Res. 1989;21(6),428-435.