Ixekizumab

TargetMol
Product Code: TAR-T38105
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T38105-1mg1mg£180.00
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TAR-T38105-5mg5mg£442.00
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TAR-T38105-10mg10mg£615.00
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TAR-T38105-25mg25mg£930.00
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TAR-T38105-50mg50mg£1,219.00
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Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A (KD<3 pM). Ixekizumab directly blocks IL-17A binding to IL-17RA (IL-17A receptor) but does not bind to other IL-17 family members. Ixekizumab is used for the research of moderate-to-severe plaque psoriasis[1][2].
CAS:
1143503-69-8
Formula:
N/A
Molecular Weight:
0
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
N/A
Target:
Interleukin|IL Receptor

References

Griffiths CE, et al. Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials. Lancet. 2015;386(9993):541-551. Liu L, et al. Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A. J Inflamm Res. 2016;9:39-50.