(S)-O-Desmethyl Venlafaxine N-Oxide
| Code | Size | Price |
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| TAR-T38134-1mg | 1mg | £173.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
(S)-O-Desmethyl Venlafaxine N-Oxide is a N-oxyde of (S)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
CAS:
1021934-03-1
Formula:
C16H25NO3
Molecular Weight:
279.37
Purity:
0.98
SMILES:
OC1=CC=C([C@H](C2(O)CCCCC2)C[N+](C)(C)[O-])C=C1
References
Lechoslaw A. Turski, et al. N-oxydes de venlafaxine et de o-desm?thylvenlafaxine comme prom?dicaments. WO2009000797A1.
F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.
Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.