Prostaglandin F2 α Ethanolamide

TargetMol
Product Code: TAR-T38195
Supplier: TargetMol
CodeSizePrice
TAR-T38195-1mg1mg£139.00
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TAR-T38195-5mg5mg£390.00
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Quantity:
TAR-T38195-10mg10mg£640.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Prostaglandin F2α ethanolamide (PGF2α-EA) is produced by COX-2 metabolism of the endogenous cannabinoid, arachidonoyl ethanolamide (AEA), found in brain, liver, and other mammalian tissues. AEA can be metabolized directly by the sequential action of COX-2 and specific PG synthases to produce ethanolamide congeners of the classical PGs. PGF2α-EA has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of living mice. PGF2α-EA is a potent dilator (EC50 = 58 nM) of the cat iris sphincter, which is a model system for testing potential intraocular hypotensive agents.
CAS:
353787-70-9
Formula:
C22H39NO5
Molecular Weight:
397.556
Purity:
0.98
SMILES:
CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C/CCCC(=O)NCCO