Guselkumab

TargetMol
Product Code: TAR-T38362
Product Group: Primary Antibodies
Supplier: TargetMol
CodeSizePrice
TAR-T38362-1mg1mg£604.00
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Quantity:
TAR-T38362-5mg5mg£1,934.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Monoclonal
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
CAS:
1350289-85-8
Formula:
N/A
Molecular Weight:
0
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
N/A
Target:
IL Receptor

References

Li L, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol. 2020;89(Pt B):107008. International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf