EB-42486

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TargetMol
Product Code: TAR-T39972
Supplier: TargetMol
CodeSizePrice
TAR-T39972-1mg1mg£171.00
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TAR-T39972-5mg5mg£322.00
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TAR-T39972-1mL1 mL * 10 mM (in DMSO)£348.00
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TAR-T39972-10mg10mg£470.00
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TAR-T39972-25mg25mg£707.00
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TAR-T39972-50mg50mg£978.00
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TAR-T39972-100mg100mg£1,291.00
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TAR-T39972-500mg500mg£2,456.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.
CAS:
2390475-81-5
Formula:
C22H22N8O
Molecular Weight:
414.46
Pathway:
Autophagy
Purity:
0.98
SMILES:
CC1(C)n2nnnc2N(C)C(C)=C1C(Nc(cc1)cc2c1[nH]nc2-c1ccccc1)=O
Target:
LRRK2

References

Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839.