TargetMol

Talatisamine

Product Code:
 
TAR-T3S1873
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3S1873-1mg1mg£118.00
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TAR-T3S1873-5mg5mg£174.00
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TAR-T3S1873-10mg10mg£246.00
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TAR-T3S1873-25mg25mg£380.00
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TAR-T3S1873-50mg50mg£515.00
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TAR-T3S1873-100mg100mg£741.00
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Further Information

Bioactivity:
1. Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. 2. Talatisamine can therefore be considered as a leading compound worthy of further investigations.
CAS:
20501-56-8
Formula:
C24H39NO5
Molecular Weight:
421.578
Pathway:
Membrane transporter/Ion channel
Purity:
0.9944
SMILES:
CCN1C[C@]2(COC)CC[C@H](OC)[C@@]34[C@@H]5C[C@H]6[C@H](O)[C@@H]5[C@](O)(C[C@@H]6OC)[C@@H](C[C@H]23)C14
Target:
Potassium Channel

References

Song M K , Liu H , Jiang H L , et al. Discovery of talatisamine as a novel specific blocker for the delayed rectifier K+ channels in rat hippocampal neurons.[J]. Neuroscience, 2008, 155(2):469-475.