KIN1148

TargetMol
Product Code: TAR-T4027
Supplier: TargetMol
CodeSizePrice
TAR-T4027-1mg1mg£180.00
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TAR-T4027-2mg2mg£254.00
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TAR-T4027-1mL1 mL * 10 mM (in DMSO)£354.00
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TAR-T4027-5mg5mg£430.00
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TAR-T4027-10mg10mg£611.00
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TAR-T4027-25mg25mg£922.00
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TAR-T4027-50mg50mg£1,219.00
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TAR-T4027-100mg100mg£1,621.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection. The adjuvant will be developed for an FDA-approved avian inluenza virus vaccine as well as evaluation in flavivirus vaccine platforms, including West Nile virus, because of the small molecules broad immune-enhancing activity.
CAS:
1428729-56-9
Formula:
C19H11N3OS2
Molecular Weight:
361.44
Pathway:
Microbiology/Virology
Purity:
0.9898
SMILES:
O=C(Nc1nc2ccc3scnc3c2s1)c1ccc2ccccc2c1
Target:
Influenza Virus

References

Probst P., et al. A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response.