TargetMol

Monastrol

Product Code:
 
TAR-T4048
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4048-1mg1mg£105.00
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TAR-T4048-2mg2mg£115.00
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TAR-T4048-5mg5mg£125.00
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TAR-T4048-10mg10mg£145.00
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TAR-T4048-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T4048-25mg25mg£223.00
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TAR-T4048-50mg50mg£328.00
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TAR-T4048-100mg100mg£529.00
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Quantity:
TAR-T4048-500mg500mg£1,075.00
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This product comes from: United States.
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Further Information

Bioactivity:
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
CAS:
329689-23-8
Formula:
C14H16N2O3S
Molecular Weight:
292.35
Pathway:
Cytoskeletal Signaling; Apoptosis
Purity:
0.9919
SMILES:
CCOC(=O)C1=C(C)N=C(S)NC1c1cccc(O)c1
Target:
Apoptosis; Kinesin

References

Cochran JC, et al. Monastrol inhibition of the mitotic kinesin Eg5. J BiolChem. 2005 Apr 1;280(13):12658-67. Marques LA, et al. Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells. Naunyn Schmiedebergs Arch Pharmacol. 2016 Dec;389(12):1279-1288.