Thalidomide-5-methyl

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TargetMol
Product Code: TAR-T40503
Supplier: TargetMol
CodeSizePrice
TAR-T40503-1mg1mg£227.00
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TAR-T40503-1mL1 mL * 10 mM (in DMSO)£390.00
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TAR-T40503-5mg5mg£422.00
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Quantity:
TAR-T40503-10mg10mg£589.00
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Quantity:
TAR-T40503-25mg25mg£863.00
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Quantity:
TAR-T40503-50mg50mg£1,179.00
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Quantity:
TAR-T40503-100mg100mg£1,564.00
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TAR-T40503-500mg500mg£3,058.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.
CAS:
40313-92-6
Formula:
C14H12N2O4
Molecular Weight:
272.26
Pathway:
PROTAC
Purity:
0.98
SMILES:
Cc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
Target:
Ligand for E3 Ligase

References

George W. Muller, et al. Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNF? levels. Patent US5874448A.