TargetMol

lavendustin A

Product Code:
 
TAR-T4183
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4183-1mg1mg£254.00
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TAR-T4183-2mg2mg£349.00
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TAR-T4183-5mg5mg£550.00
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TAR-T4183-10mg10mg£755.00
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TAR-T4183-25mg25mg£1,107.00
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TAR-T4183-50mg50mg£1,460.00
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This product comes from: United States.
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Further Information

Bioactivity:
lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
CAS:
125697-92-9
Formula:
C21H19NO6
Molecular Weight:
381.384
Pathway:
Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors; Proteases/Proteasome
Purity:
0.98
SMILES:
OC(=O)c1cc(ccc1O)N(Cc1ccccc1O)Cc1cc(O)ccc1O
Target:
EGFR; Tyrosinase

References

Lee KY, et al. Synthesis and anticancer activity of lavendustin A derivatives containing arylethenylchromone substituents. Eur J Med Chem. 2006 Aug;41(8):1991-6 L?ber K, et al. Influence of the tyrosine kinase inhibitors STI571 (Glivec), lavendustin A and genistein on human mast cell line (HMC-1(560)) activation. J Cell Biochem. 2008 Mar 1;103(4):1076-88 Nam DH, et al. Synthesis and anticancer activity of chromone-based analogs of lavendustin A. Eur J Med Chem. 2010 Sep;45(9):4288-92