Desmethyl-VS-5584

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TargetMol
Product Code: TAR-T4199
Supplier: TargetMol
CodeSizePrice
TAR-T4199-1mg1mg£114.00
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TAR-T4199-2mg2mg£148.00
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TAR-T4199-5mg5mg£193.00
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TAR-T4199-10mg10mg£287.00
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TAR-T4199-25mg25mg£434.00
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TAR-T4199-50mg50mg£607.00
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TAR-T4199-100mg100mg£833.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.
CAS:
1246535-95-4
Formula:
C16H20N8O
Molecular Weight:
340.391
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9891
SMILES:
CC(C)n1cnc2c(nc(nc12)N1CCOCC1)-c1cnc(N)nc1
Target:
PI3K; mTOR

References

Shao Z,et al. VS-5584, a Novel PI3K-mTOR Dual Inhibitor, Inhibits Melanoma Cell Growth In Vitro and In Vivo. PLoS One. 2015 Jul 23;10(7). Kolev VN, et al. PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells. Cancer Res. 2015 Jan 15;75(2):446-55.