Prexasertib

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TargetMol
Product Code: TAR-T4310
Supplier: TargetMol
CodeSizePrice
TAR-T4310-1mg1mg£109.00
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TAR-T4310-2mg2mg£139.00
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TAR-T4310-5mg5mg£173.00
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TAR-T4310-10mg10mg£242.00
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TAR-T4310-25mg25mg£414.00
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TAR-T4310-50mg50mg£571.00
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TAR-T4310-100mg100mg£779.00
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TAR-T4310-500mg500mg£1,484.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Prexasertib is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
CAS:
1234015-52-1
Formula:
C18H19N7O2
Molecular Weight:
365.397
Pathway:
Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9728
SMILES:
COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Target:
Apoptosis; Chk

References

Yin Y, et al. Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer. Am J Cancer Res. 2017 Mar 1;7(3):473-483. King C, et al. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Mol Cancer Ther. 2015 Sep;14(9):2004-13