evobrutinib

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TargetMol
Product Code: TAR-T4387
Supplier: TargetMol
CodeSizePrice
TAR-T4387-1mg1mg£114.00
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TAR-T4387-2mg2mg£124.00
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TAR-T4387-1mL1 mL * 10 mM (in DMSO)£146.00
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TAR-T4387-5mg5mg£146.00
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TAR-T4387-10mg10mg£197.00
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TAR-T4387-25mg25mg£324.00
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TAR-T4387-50mg50mg£450.00
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TAR-T4387-100mg100mg£627.00
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TAR-T4387-500mg500mg£1,243.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Evobrutinib, also known as M-2951 and MSC-2364447C, is a highly selective inhibitor of the Bruton's tyrosine kinase (BTK), which is important in the development and functioning of various immune cells including B -lymphocytes and macrophages. PreClinical research suggests it may be therapeutically useful in certain autoimmune diseases.
CAS:
1415823-73-2
Formula:
C25H27N5O2
Molecular Weight:
429.524
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9942
SMILES:
Nc1ncnc(NCC2CCN(CC2)C(=O)C=C)c1-c1ccc(Oc2ccccc2)cc1
Target:
BTK

References

Li Z, et al. Drug Test Anal. 2018, doi: 10.12002/dta.2477. Crawford JJ, et al. J Med Chem. 2018, 61(6):2227-2245.