DAMGO TFA (78123-71-4(Free base))
Code | Size | Price |
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TAR-T4411-1mg | 1mg | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4411-2mg | 2mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4411-5mg | 5mg | £209.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4411-10mg | 10mg | £310.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4411-25mg | 25mg | £526.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4411-50mg | 50mg | £694.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Potent, selective agonist of Mu-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats.
CAS:
T4411
Formula:
C28H36F3N5O8
Molecular Weight:
627.6
Pathway:
Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Purity:
0.9867
SMILES:
OC(=O)C(F)(F)F.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO
Target:
Opioid Receptor
References
Happel C,etal.DAMGO-induced expression of chemokines and chemokine receptors: the role of TGF-beta1.J Leukoc Biol. 2008 Apr;83(4):956-63.
Onogi T,etal.DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops.FEBS Lett. 1995 Jan 2;357(1):93-7.
Rubovitch V,etal.The mu opioid agonist DAMGO stimulates cAMP production in SK-N-SH cells through a PLC-PKC-Ca++ pathway.Brain Res Mol Brain Res. 2003 Feb 20;110(2):261-6.
Selve N,etal.Galanin receptor antagonists attenuate spinal antinociceptive effects of DAMGO, tramadol and non-opioid drugs in rats.Brain Res. 1996 Oct 7;735(2):177-87.
Szab? G,etal.Long-lasting antinociceptive effect of DAMGO chloromethyl ketone in rats.Peptides. 1999 Nov;20(11):1321-6.