TargetMol

Licochalcone B

Product Code:
 
TAR-T4S0350
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S0350-1mg1mg£109.00
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TAR-T4S0350-5mg5mg£166.00
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TAR-T4S0350-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T4S0350-10mg10mg£230.00
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TAR-T4S0350-25mg25mg£349.00
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TAR-T4S0350-50mg50mg£484.00
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TAR-T4S0350-100mg100mg£670.00
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Further Information

Bioactivity:
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licochalcone D(LCD) significantly reduced the LPS-induced production of NO, TNFalpha and MCP-1. 3. A novel LCB derivative compound: (E)-3-(3, 4-dihydroxy-2-methoxyphenyl)-1-(2, 4-dihydroxyphenyl)prop-2-en-1-one inhibits inflammatory reactions in macrophages and protects mice from endotoxin shock.
CAS:
58749-23-8
Formula:
C16H14O5
Molecular Weight:
286.283
Pathway:
; Neuroscience
Purity:
0.999
SMILES:
COc1c(O)c(O)ccc1C=CC(=O)c1ccc(O)cc1
Target:
Beta Amyloid;

References

Yuan X, Li T, Xiao E, et al. Licochalcone B inhibits growth of bladder cancer cells by arresting cell cycle progression and inducing apoptosis[J]. Food & Chemical Toxicology, 2014, 65(1):242-251.