TargetMol

Furanodienone

Product Code:
 
TAR-T4S0544
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4S0544-1mg1mg£114.00
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TAR-T4S0544-1mL1 mL * 10 mM (in DMSO)£163.00
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TAR-T4S0544-5mg5mg£169.00
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TAR-T4S0544-10mg10mg£217.00
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TAR-T4S0544-25mg25mg£309.00
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TAR-T4S0544-50mg50mg£431.00
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This product comes from: United States.
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Further Information

Bioactivity:
1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
CAS:
24268-41-5
Formula:
C15H18O2
Molecular Weight:
230.307
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling; Apoptosis
Purity:
0.9832
SMILES:
Cc1coc2CC(C)=CCCC(C)=CC(=O)c12
Target:
Apoptosis; HER

References

Li Y W , Zhu G Y , Shen X L , et al. Furanodienone induces cell cycle arrest and apoptosis by suppressing EGFR/HER2 signaling in HER2-overexpressing human breast cancer cells[J]. Cancer Chemother Pharmacol, 2011, 68(5):1315-1323.