Berberrubine chloride
| Code | Size | Price |
|---|
| TAR-T4S0795-1mL | 1 mL * 10 mM (in DMSO) | £127.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4S0795-20mg | 20mg | £175.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
CAS:
15401-69-1
Formula:
C19H16ClNO4
Molecular Weight:
357.79
Pathway:
Immunology/Inflammation
Purity:
0.9781
SMILES:
[Cl-].COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1O
Target:
IL Receptor
References
Cui H S , Hayasaka S , Zhang X Y , et al. Effect of berberrubine on interleukin-8 and monocyte chemotactic protein-1 expression in human retinal pigment epithelial cell line[J]. Life Sciences, 2006, 79(10):0-956.
He X, Cui J, Ma H, et al.Berberrubine is a novel and selective IMPDH2 inhibitor that impairs the growth of colorectal cancer.Biochemical Pharmacology.2023: 115868.