TargetMol

Pristimerin

Product Code:
 
TAR-T4S1050
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S1050-1mg1mg£97.00
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TAR-T4S1050-5mg5mg£130.00
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TAR-T4S1050-10mg10mg£174.00
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TAR-T4S1050-25mg25mg£306.00
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TAR-T4S1050-50mg50mg£492.00
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TAR-T4S1050-100mg100mg£671.00
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TAR-T4S1050-500mg500mg£1,291.00
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Further Information

Bioactivity:
1. Pristimerin has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells. 2. Pristimerin down-regulates the expression of pro-inflammatory mediators through blocking of NF-κB activation by inhibiting interconnected ROS/IKK/NF-κB signaling pathways, can effectively inhibit both arthritic inflammation and cartilage and bone damage in the joints.
CAS:
1258-84-0
Formula:
C30H40O4
Molecular Weight:
464.646
Pathway:
Microbiology/Virology; NF-κb
Purity:
0.9959
SMILES:
COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
Target:
NF-κB; Antibacterial

References

Zuo J , Guo Y , Peng X , et al. Inhibitory action of pristimerin on hypoxia?mediated metastasis involves stem cell characteristics and EMT in PC-3 prostate cancer cells[J]. Oncology Reports, 2015, 33(3):1388-94.