TargetMol

Sanggenon C

Product Code:
 
TAR-T4S1615
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T4S1615-1mg1mg£148.00
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TAR-T4S1615-5mg5mg£269.00
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TAR-T4S1615-1mL1 mL * 10 mM (in DMSO)£351.00
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TAR-T4S1615-10mg10mg£366.00
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TAR-T4S1615-25mg25mg£547.00
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TAR-T4S1615-50mg50mg£752.00
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TAR-T4S1615-100mg100mg£1,002.00
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Further Information

Bioactivity:
1. Sanggenone C inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenone C and O inhibited NO production and iNOS expression by suppressing NF-κB activity and IκBα activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB.
CAS:
80651-76-9
Formula:
C40H36O12
Molecular Weight:
708.716
Pathway:
NF-κb
Purity:
0.9776
SMILES:
CC(C)=CCC12Oc3cc(O)c([C@H]4C=C(C)C[C@@H]([C@H]4C(=O)c4ccc(O)cc4O)c4ccc(O)cc4O)c(O)c3C(=O)C1(O)Oc1cc(O)ccc21
Target:
NF-κB

References

Huang H , Liu N , Zhao K , et al. Sanggenon C decreases tumor cell viability associated with proteasome inhibition[J]. Front Biosci, 2011, 3(4):1315-1325.