AIM-100

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TargetMol
Product Code: TAR-T5092
Supplier: TargetMol
CodeSizePrice
TAR-T5092-1mg1mg£103.00
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TAR-T5092-2mg2mg£118.00
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TAR-T5092-5mg5mg£144.00
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Quantity:
TAR-T5092-1mL1 mL * 10 mM (in DMSO)£149.00
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Quantity:
TAR-T5092-10mg10mg£164.00
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Quantity:
TAR-T5092-25mg25mg£274.00
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Quantity:
TAR-T5092-50mg50mg£468.00
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TAR-T5092-100mg100mg£653.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AIM-100 is a Ack1 inhibitor (IC50: 24 nM).
CAS:
873305-35-2
Formula:
C23H21N3O2
Molecular Weight:
371.44
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9875
SMILES:
C(Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)[C@@H]1CCCO1
Target:
ACK

References

Mahajan K, et al. Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. J Biol Chem. 2012 Jun 22;287(26):22112-22. Mahajan K, et al. Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Prostate. 2010 Sep 1;70(12):1274-85. Mahajan K, et al. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol. 2012 Apr;180(4):1386-93.