Avapritinib

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TargetMol
Product Code: TAR-T5109
Supplier: TargetMol
CodeSizePrice
TAR-T5109-1mg1mg£135.00
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TAR-T5109-5mg5mg£229.00
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TAR-T5109-1mL1 mL * 10 mM (in DMSO)£244.00
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TAR-T5109-10mg10mg£329.00
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TAR-T5109-25mg25mg£510.00
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TAR-T5109-50mg50mg£703.00
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TAR-T5109-100mg100mg£938.00
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TAR-T5109-500mg500mg£1,821.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Avapritinib is a dual inhibitor of the mutant KIT receptor (KIT D816V, IC50: 0.27 nM) and PDGFRα (PDGFRα D842V, IC50: 0.24 nM).
CAS:
1703793-34-3
Formula:
C26H27FN10
Molecular Weight:
498.57
Pathway:
Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.995
SMILES:
Cn1cc(cn1)-c1cc2c(ncnn2c1)N1CCN(CC1)c1ncc(cn1)[C@@](C)(N)c1ccc(F)cc1
Target:
PDGFR; c-Kit

References

Erica Evans, et al. Blu-285, a Potent and Selective Inhibitor for Hematologic Malignancies with KIT Exon 17 Mutations.Blood 2015 126:568.