TD139

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TargetMol
Product Code: TAR-T5121
Supplier: TargetMol
CodeSizePrice
TAR-T5121-1mg1mg£149.00
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TAR-T5121-2mg2mg£201.00
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TAR-T5121-5mg5mg£293.00
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TAR-T5121-10mg10mg£431.00
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Quantity:
TAR-T5121-25mg25mg£611.00
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TAR-T5121-50mg50mg£840.00
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TAR-T5121-100mg100mg£1,107.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
TD139 is an inhaled galectin-3 inhibitor (Kd: 14 nM).
CAS:
1450824-22-2
Formula:
C28H30F2N6O8S
Molecular Weight:
648.64
Pathway:
Immunology/Inflammation
Purity:
0.9948
SMILES:
OC[C@H]1O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)-c2cccc(F)c2)[C@H](O)[C@H]([C@H]1O)n1cc(nn1)-c1cccc(F)c1
Target:
Galectin

References

Mackinnon AC, et al. Regulation of transforming growth factor-?1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med. 2012 Mar 1;185(5):537-46. Liu Y, Zhao C, Meng J, et al. Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis. Clinical Immunology. 2022: 108939. Volarevic V, et al. Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice. Hepatology. 2012 Jun;55(6):1954-64.