T-26c

TargetMol
Product Code: TAR-T5361
Supplier: TargetMol
CodeSizePrice
TAR-T5361-1mg1mg£103.00
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TAR-T5361-2mg2mg£117.00
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TAR-T5361-5mg5mg£148.00
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TAR-T5361-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T5361-10mg10mg£195.00
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TAR-T5361-25mg25mg£282.00
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TAR-T5361-50mg50mg£430.00
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TAR-T5361-100mg100mg£589.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).
CAS:
869296-13-9
Formula:
C24H21N3O6S
Molecular Weight:
479.51
Pathway:
Proteases/Proteasome
Purity:
1
SMILES:
COc1cccc(CNC(=O)c2nc(=O)c3c(COCc4ccc(cc4)C(O)=O)csc3[nH]2)c1
Target:
MMP

References

Nara H, et al. Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1? binding site. Bioorg Med Chem. 2014 Oct 1;22(19):5487-505.