TargetMol

BAY-293

Product Code:
 
TAR-T5418
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5418-1mg1mg£109.00
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TAR-T5418-5mg5mg£161.00
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TAR-T5418-1mL1 mL * 10 mM (in DMSO)£171.00
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TAR-T5418-10mg10mg£229.00
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TAR-T5418-25mg25mg£389.00
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TAR-T5418-50mg50mg£544.00
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Quantity:
TAR-T5418-100mg100mg£748.00
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This product comes from: United States.
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Further Information

Bioactivity:
BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction (IC50: 21 nM).
CAS:
2244904-70-7
Formula:
C25H28N4O2S
Molecular Weight:
448.59
Pathway:
GPCR/G Protein; MAPK
Purity:
0.968
SMILES:
CNCc1ccccc1-c1csc(c1)[C@@H](C)Nc1nc(C)nc2cc(OC)c(OC)cc12
Target:
Raf; Ras

References

Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.