ILK-IN-2

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TargetMol
Product Code: TAR-T5488
Supplier: TargetMol
CodeSizePrice
TAR-T5488-1mg1mg£124.00
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TAR-T5488-2mg2mg£148.00
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TAR-T5488-5mg5mg£203.00
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TAR-T5488-10mg10mg£244.00
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TAR-T5488-1mL1 mL * 10 mM (in DMSO)£257.00
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TAR-T5488-25mg25mg£291.00
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TAR-T5488-50mg50mg£343.00
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TAR-T5488-100mg100mg£466.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
OSU-T315 is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.
CAS:
1333146-24-9
Formula:
C30H30F3N5O
Molecular Weight:
533.599
Pathway:
Cytoskeletal Signaling
Purity:
0.9931
SMILES:
CNC(=O)CCc1cc(-c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)N1CCNCC1
Target:
Integrin

References

Liu TM, et al. OSU-T315: a novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cells. Blood. 2015 Jan 8;125(2):284-95. Lee SL, et al. Identification and characterization of a novel integrin-linked kinase inhibitor. J Med Chem. 2011 Sep 22;54(18):6364-74.