Belvarafenib

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TargetMol
Product Code: TAR-T5634
Supplier: TargetMol
CodeSizePrice
TAR-T5634-1mg1mg£103.00
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TAR-T5634-2mg2mg£115.00
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TAR-T5634-5mg5mg£148.00
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TAR-T5634-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T5634-10mg10mg£209.00
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TAR-T5634-25mg25mg£302.00
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TAR-T5634-50mg50mg£414.00
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TAR-T5634-100mg100mg£582.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.
CAS:
1446113-23-0
Formula:
C23H16ClFN6OS
Molecular Weight:
478.93
Pathway:
MAPK
Purity:
0.9962
SMILES:
Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12
Target:
Raf

References

Son J B , Jung S H , Choi Ii W , et al. Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases[J]. 2015.