BMS-1166

TargetMol
Product Code: TAR-T5697
Supplier: TargetMol
CodeSizePrice
TAR-T5697-1mg1mg£142.00
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TAR-T5697-2mg2mg£171.00
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TAR-T5697-5mg5mg£223.00
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TAR-T5697-1mL1 mL * 10 mM (in DMSO)£290.00
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TAR-T5697-10mg10mg£321.00
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TAR-T5697-25mg25mg£536.00
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Quantity:
TAR-T5697-50mg50mg£736.00
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TAR-T5697-100mg100mg£994.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.
CAS:
1818314-88-3
Formula:
C36H33ClN2O7
Molecular Weight:
641.12
Pathway:
Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
Purity:
0.9914
SMILES:
Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
Target:
PD-1/PD-L1

References

Skalniak L , Zak K M , Guzik K , et al. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells[J]. Oncotarget, 2017, 8(42).