7-Epi 10-desacetyl paclitaxel
Code | Size | Price |
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TAR-T5738-10mg | 10mg | £159.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
7-Epi-10-deacetyltaxol shows IC50 values of 0.085 nM, against HeLa cells.
CAS:
78454-17-8
Formula:
C45H49NO13
Molecular Weight:
811.881
Purity:
0.9805
SMILES:
[H][C@@]12C[C@@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1
References
Dang P H , Nguyen H X , Duong T T T , et al. ?-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of
,?Taxus wallichiana[J]. Journal of Natural Products, 2017:acs.jnatprod.7b00006.
Subban K , Singh S , Subramani R , et al. Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2)[J]. BMC Complementary and Alternative Medicine, 2017, 17(1):504.