Paederosidic acid
| Code | Size | Price |
|---|
| TAR-T5739-1mL | 1 mL * 10 mM (in DMSO) | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T5739-10mg | 10mg | £175.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GAD 65, may be a promising future therapeutic agent for treatment of epilepsy.
CAS:
18842-98-3
Formula:
C18H24O12S
Molecular Weight:
464.44
Pathway:
Apoptosis
Purity:
0.9996
SMILES:
[H][C@]12[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C(C(O)=O)[C@@]1([H])[C@@H](O)C=C2COC(=O)SC
Target:
Apoptosis; BCL
References
Yang T , Kong B , Gu J W , et al. Anticonvulsant and Sedative Effects of Paederosidic Acid isolated from Paederia scandens (Lour.) Merrill. in Mice and Rats[J]. Pharmacology Biochemistry and Behavior, 2013, 111.
Yu P , Shi L , Song M , et al. Antitumor activity of paederosidic acid in human non-small cell lung cancer cells via inducing mitochondria-mediated apoptosis[J]. Chemico-Biological Interactions, 2017, 269:33-40.