TargetMol

Rotundic acid

Product Code:
 
TAR-T5S0506
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S0506-1mg1mg£99.00
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TAR-T5S0506-5mg5mg£132.00
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TAR-T5S0506-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T5S0506-10mg10mg£157.00
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TAR-T5S0506-25mg25mg£214.00
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TAR-T5S0506-50mg50mg£284.00
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Quantity:
TAR-T5S0506-100mg100mg£388.00
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This product comes from: United States.
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Further Information

Bioactivity:
Rotundic acid, a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) cell lines.
CAS:
20137-37-5
Formula:
C30H48O5
Molecular Weight:
488.709
Pathway:
PI3K/Akt/mTOR signaling; MAPK; ; Cytoskeletal Signaling; Apoptosis
Purity:
0.9843
SMILES:
C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@]1(C)O)C(O)=O
Target:
Apoptosis; p38 MAPK; Akt; mTOR

References

Wei H, Guo J, Sun X, et al. Discovery of Natural Ursane-type SENP1 Inhibitors and the Platinum Resistance Reversal Activity Against Human Ovarian Cancer Cells: A Structure?Activity Relationship Study. Journal of Natural Products. 2022