Corynoxine

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TargetMol
Product Code: TAR-T5S0658
Supplier: TargetMol
CodeSizePrice
TAR-T5S0658-1mg1mg£103.00
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TAR-T5S0658-5mg5mg£143.00
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TAR-T5S0658-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T5S0658-10mg10mg£173.00
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TAR-T5S0658-25mg25mg£243.00
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TAR-T5S0658-50mg50mg£326.00
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TAR-T5S0658-100mg100mg£447.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Corynoxine is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
CAS:
6877-32-3
Formula:
C22H28N2O4
Molecular Weight:
384.476
Pathway:
Autophagy
Purity:
0.9921
SMILES:
CC[C@@H]1CN2CC[C@]3([C@@H]2C[C@@H]1C(=C/OC)C(=O)OC)C(=O)Nc1ccccc31
Target:
Autophagy

References

Chen LL, et al. Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway. J Neuroimmune Pharmacol. 2014 Jun;9(3):380-7. Sakakibara I, et al. Effect on locomotion of indole alkaloids from the hooks of uncaria plants. Phytomedicine. 1999 Jul;6(3):163-8.