TargetMol

Demethylwedelolactone

Product Code:
 
TAR-T5S0689
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S0689-1mg1mg£102.00
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Quantity:
TAR-T5S0689-1mL1 mL * 10 mM (in DMSO)£169.00
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TAR-T5S0689-5mg5mg£173.00
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TAR-T5S0689-10mg10mg£242.00
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Quantity:
TAR-T5S0689-25mg25mg£359.00
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Quantity:
TAR-T5S0689-50mg50mg£500.00
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Further Information

Bioactivity:
Demethylwedelolactone is a natural product isolated from Eclipta alba, has trypsin inhibitory effect an IC50 of 3.0 μM. it exerts anti-invasive growth effect on breast cancer cells.
CAS:
6468-55-9
Formula:
C15H8O7
Molecular Weight:
300.222
Pathway:
Proteases/Proteasome
Purity:
0.998
SMILES:
Oc1cc(O)c2c3oc4cc(O)c(O)cc4c3c(=O)oc2c1
Target:
Serine Protease

References

Trypsin inhibitory effect of wedelolactone and demethylwedelolactone. Phytother Res. 2003 Apr;17(4):420-1. Demethylwedelolactone derivatives inhibit invasive growth in vitro and lung metastasis of MDA-MB-231 breast cancer cells in nude mice. Eur J Med Chem. 2012 Oct;56:361-7.