TargetMol

Kurarinone

Product Code:
 
TAR-T5S0993
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S0993-1mg1mg£102.00
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TAR-T5S0993-5mg5mg£168.00
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TAR-T5S0993-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T5S0993-10mg10mg£229.00
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TAR-T5S0993-25mg25mg£436.00
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TAR-T5S0993-50mg50mg£598.00
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TAR-T5S0993-100mg100mg£808.00
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TAR-T5S0993-500mg500mg£1,540.00
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Further Information

Bioactivity:
Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameliorate chronic inflammatory skin diseases through the suppression of pathogenic CD4(+) T-cell differentiation and the overall immune response.
CAS:
34981-26-5
Formula:
C26H30O6
Molecular Weight:
438.52
Pathway:
JAK/STAT signaling; NF-κb; Chromatin/Epigenetic; Apoptosis; ; Stem Cells; Angiogenesis
Purity:
0.9972
SMILES:
COc1cc(O)c(C[C@@H](CC=C(C)C)C(C)=C)c2O[C@@H](CC(=O)c12)c1ccc(O)cc1O
Target:
BCL; IκB/IKK; TNF; NF-κB; JAK; STAT

References

Estrogenic and anticarcinogenic properties of kurarinone, a lavandulyl flavanone from the roots of Sophora flavescens. J. Nat.Prod., 2004, 67(11):1829-32.