TargetMol

Apigenin-7-glucuronide

Product Code:
 
TAR-T5S1026
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1026-1mg1mg£120.00
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TAR-T5S1026-5mg5mg£177.00
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TAR-T5S1026-1mL1 mL * 10 mM (in DMSO)£189.00
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TAR-T5S1026-10mg10mg£252.00
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TAR-T5S1026-25mg25mg£389.00
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TAR-T5S1026-50mg50mg£550.00
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TAR-T5S1026-100mg100mg£752.00
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Further Information

Bioactivity:
Apigenin-7-glucuronide possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively).
CAS:
29741-09-1
Formula:
C21H18O11
Molecular Weight:
446.364
Pathway:
Proteases/Proteasome
Purity:
0.9927
SMILES:
O[C@H]1[C@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O
Target:
MMP

References

Hu W, et al. Apigenin-7-O-?-D-glucuronide inhibits LPS-induced inflammation through the inactivation of AP-1 and MAPK signaling pathways in RAW 264.7 macrophages and protects mice against endotoxin shock. Food Funct. 2016 Feb;7(2):1002-13. Crasc? L, et al. Correlating In Vitro Target-Oriented Screening and Docking: Inhibition of Matrix Metalloproteinases Activities by Flavonoids. Planta Med. 2017 Jul;83(11):901-911.