TargetMol

Isoliensinine

Product Code:
 
TAR-T5S1103
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1103-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T5S1103-20mg20mg£175.00
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Further Information

Bioactivity:
1. Isoliensinine, a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. 2. Isoliensinine possesses an anti-proliferative effect, which is related to the decrease of the overexpression of growth factors PDGF-beta, bFGF, proto-oncogene c-fos, c-myc and hsp7.
CAS:
6817-41-0
Formula:
C37H42N2O6
Molecular Weight:
610.751
Pathway:
oxidation-reduction; Apoptosis
Purity:
0.9853
SMILES:
COc1ccc(C[C@H]2N(C)CCc3cc(OC)c(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(O)cc56)ccc4O)cc23)cc1
Target:
Apoptosis; Antioxidant

References

Zhang X , Wang X , Wu T , et al. Isoliensinine induces apoptosis in triple-negative human breast cancer cells through ROS generation and p38 MAPK/JNK activation[J]. Scientific Reports, 2015, 5:12579.