TargetMol

Cucurbitacin E

Product Code:
 
TAR-T5S1467
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1467-1mg1mg£114.00
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TAR-T5S1467-5mg5mg£164.00
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TAR-T5S1467-1mL1 mL * 10 mM (in DMSO)£185.00
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TAR-T5S1467-10mg10mg£221.00
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TAR-T5S1467-25mg25mg£324.00
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TAR-T5S1467-50mg50mg£447.00
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TAR-T5S1467-100mg100mg£614.00
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Further Information

Bioactivity:
Cucurbitacin E is a natural product isolated from the climbing stem of Cucumic melo L. It significantly suppresses the activity of the cyclin B1/CDC2 complex.Cucurbitacin E has prevention of neurodegeneration, it has potent anti-proliferative, antineoplastic, anti-inflammatory and analgesic actions.
CAS:
18444-66-1
Formula:
C32H44O8
Molecular Weight:
556.696
Pathway:
Cell Cycle/Checkpoint; Autophagy
Purity:
0.9888
SMILES:
[H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C=C(O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)C=CC(C)(C)OC(C)=O
Target:
CDK; Autophagy

References

Y-C, Hsu, T-Y, et al. Therapeutic ROS targeting of GADD45? in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E.[J]. Cell Death & Disease, 2014.