FINO2

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TargetMol
Product Code: TAR-T60084
Supplier: TargetMol
CodeSizePrice
TAR-T60084-1mg1mg£114.00
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TAR-T60084-5mg5mg£177.00
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TAR-T60084-10mg10mg£244.00
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TAR-T60084-25mg25mg£365.00
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Quantity:
TAR-T60084-50mg50mg£510.00
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Quantity:
TAR-T60084-100mg100mg£736.00
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Quantity:
TAR-T60084-200mg200mg£1,075.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation.
CAS:
869298-31-7
Formula:
C15H28O3
Molecular Weight:
256.38
Pathway:
Apoptosis; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
C(CO)C1(C)C[C@]2(OO1)CC[C@@H]([C@@](C)(C)C)CC2
Target:
Ferroptosis

References

Gaschler MM, et al. FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol. 2018 May;14(5):507-515.