Nutlin-3a

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TargetMol
Product Code: TAR-T6023
Supplier: TargetMol
CodeSizePrice
TAR-T6023-1mg1mg£107.00
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TAR-T6023-2mg2mg£122.00
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TAR-T6023-5mg5mg£148.00
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TAR-T6023-1mL1 mL * 10 mM (in DMSO)£181.00
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TAR-T6023-10mg10mg£205.00
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TAR-T6023-25mg25mg£297.00
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TAR-T6023-50mg50mg£406.00
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TAR-T6023-100mg100mg£567.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Nutlin-3a, the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.
CAS:
675576-98-4
Formula:
C30H30Cl2N4O4
Molecular Weight:
581.49
Pathway:
Apoptosis; Ubiquitination; Autophagy
Purity:
0.9873
SMILES:
COc1ccc(C2=N[C@H]([C@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
Target:
Apoptosis; E1/E2/E3 Enzyme; Autophagy

References

Tovar C, et al. Proc Natl Acad Sci U S A, 2006, 103(6), 1888-1893. Ohnstad HO, et al. BMC Cancer, 2011, 11(211), 1-11. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.