Zotarolimus

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TargetMol
Product Code: TAR-T6033
Supplier: TargetMol
CodeSizePrice
TAR-T6033-1mg1mg£119.00
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TAR-T6033-2mg2mg£141.00
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TAR-T6033-5mg5mg£189.00
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TAR-T6033-10mg10mg£261.00
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TAR-T6033-1mL1 mL * 10 mM (in DMSO)£272.00
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TAR-T6033-25mg25mg£402.00
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TAR-T6033-50mg50mg£548.00
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TAR-T6033-100mg100mg£763.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).
CAS:
221877-54-9
Formula:
C52H79N5O12
Molecular Weight:
966.21
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
[H][C@@]12CCCCN1C(=O)C(=O)[C@]1(O)O[C@@H](CC[C@H]1C)C[C@H](OC)C(C)=CC=CC=C[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)C(C)=C[C@@H](C)C(=O)C[C@H](OC2=O)[C@H](C)C[C@@H]1CC[C@@H]([C@@H](C1)OC)N1C=NN=N1
Target:
mTOR

References

Chen YW, et al. J Cardiovasc Pharmacol, 2007, 49(4), 228-235. Garcia-Touchard A, et al. Eur Heart J, 2006, 27(8), 988-1993.