MK-5108

Contact us
TargetMol
Product Code: TAR-T6068
Supplier: TargetMol
CodeSizePrice
TAR-T6068-1mg1mg£98.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-5mg5mg£135.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-1mL1 mL * 10 mM (in DMSO)£136.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-10mg10mg£182.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-25mg25mg£262.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-50mg50mg£369.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6068-100mg100mg£517.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1
❮❯

Documents

Further Information

Bioactivity:
MK-5108 is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.
CAS:
1010085-13-8
Formula:
C22H21ClFN3O3S
Molecular Weight:
461.94
Pathway:
Chromatin/Epigenetic; Autophagy; Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
OC(=O)[C@@]1(Cc2cccc(Nc3nccs3)n2)CC[C@@H](CC1)Oc1cccc(Cl)c1F
Target:
Aurora Kinase; Autophagy

References

Shan W, et al. Clin Cancer Res. 2012, 18(12), 3352-3365. Shimomura T, et al. Mol Cancer Ther. 2010, 9(1), 157-166.