NVP-ADW742

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TargetMol
Product Code: TAR-T6079
Supplier: TargetMol
CodeSizePrice
TAR-T6079-1mg1mg£109.00
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TAR-T6079-2mg2mg£125.00
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TAR-T6079-5mg5mg£156.00
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TAR-T6079-1mL1 mL * 10 mM (in DMSO)£157.00
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TAR-T6079-10mg10mg£213.00
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TAR-T6079-25mg25mg£328.00
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TAR-T6079-50mg50mg£545.00
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TAR-T6079-100mg100mg£748.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.
CAS:
475488-23-4
Formula:
C28H31N5O
Molecular Weight:
453.59
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis
Purity:
0.9979
SMILES:
Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)C1CC(CN2CCCC2)C1
Target:
Apoptosis; IGF-1R

References

Mitsiades CS, et al. Cancer Cell, 2004, 5(3), 221-230.