MK-2461

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TargetMol
Product Code: TAR-T6094
Supplier: TargetMol
CodeSizePrice
TAR-T6094-1mg1mg£114.00
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TAR-T6094-2mg2mg£132.00
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TAR-T6094-5mg5mg£191.00
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TAR-T6094-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T6094-10mg10mg£282.00
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TAR-T6094-25mg25mg£497.00
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TAR-T6094-50mg50mg£687.00
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TAR-T6094-100mg100mg£930.00
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TAR-T6094-500mg500mg£1,797.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
MK-2461 is a novel ATP-competitive multitargeted inhibitor of activated c-Met with a mean IC50 of 2.5 nM.
CAS:
917879-39-1
Formula:
C24H25N5O5S
Molecular Weight:
495.55
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9836
SMILES:
Cn1cc(cn1)c1cnc2ccc3c(cc(cc3)NS(=O)(=O)N(C)C[C@@H]3COCCO3)c(=O)c2c1
Target:
c-Met/HGFR

References

Park YW, et al. Anal Biochem, 1999, 269(1), 94-104. Pan BS, et al. Cancer Res, 2010, 70(4), 1524-1533.