Setanaxib

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TargetMol
Product Code: TAR-T6099
Supplier: TargetMol
CodeSizePrice
TAR-T6099-2mg2mg£98.00
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TAR-T6099-5mg5mg£115.00
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TAR-T6099-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T6099-10mg10mg£148.00
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TAR-T6099-25mg25mg£220.00
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TAR-T6099-50mg50mg£340.00
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TAR-T6099-100mg100mg£499.00
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TAR-T6099-500mg500mg£994.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GKT137831 is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
CAS:
1218942-37-0
Formula:
C21H19ClN4O2
Molecular Weight:
394.86
Pathway:
Apoptosis; Immunology/Inflammation; Cell Cycle/Checkpoint; Metabolism
Purity:
0.9672
SMILES:
CN(C)c1cccc(c1)-c1n(C)c(=O)cc2[nH]n(-c3ccccc3Cl)c(=O)c12
Target:
NADPH-oxidase; Ferroptosis; NADPH

References

Aoyama T, et al. Hepatology. 2012, 56(6), 2316-2327. Zhao QD, et al. 2015, Doi:10.1161/CIRCULATIONAHA.114. 2011079. Gray SP, et al. Circulation. 2013, 127(18), 1888-1902. Green DE, et al. Am J Respir Cell Mol Biol. 2012, 47(5), 718-726.