TargetMol

Idasanutlin

Product Code:
 
TAR-T6254
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6254-2mg2mg£100.00
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TAR-T6254-5mg5mg£117.00
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TAR-T6254-1mL1 mL * 10 mM (in DMSO)£133.00
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TAR-T6254-10mg10mg£148.00
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TAR-T6254-25mg25mg£201.00
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TAR-T6254-50mg50mg£262.00
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Quantity:
TAR-T6254-100mg100mg£390.00
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This product comes from: United States.
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Further Information

Bioactivity:
Idasanutlin (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
CAS:
1229705-06-9
Formula:
C31H29Cl2F2N3O4
Molecular Weight:
616.49
Pathway:
Ubiquitination; Apoptosis
Purity:
0.9955
SMILES:
COc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]1c1cccc(Cl)c1F)c1ccc(Cl)cc1F)C(O)=O
Target:
Mdm2; E1/E2/E3 Enzyme

References

Higgins B, et al. Clin Cancer Res. 2014, 20(14), 3742-3752. Ding Q, et al. J Med Chem. 2013, 56(14), 5979-5983. Vollmer J, Ecker J, Hielscher T, et al.Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells.Journal of Neuro-Oncology.2023: 1-16.