1-Azakenpaullone

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TargetMol
Product Code: TAR-T6358
Supplier: TargetMol
CodeSizePrice
TAR-T6358-1mg1mg£128.00
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TAR-T6358-2mg2mg£152.00
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TAR-T6358-1mL1 mL * 10 mM (in DMSO)£228.00
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TAR-T6358-5mg5mg£230.00
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TAR-T6358-10mg10mg£334.00
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TAR-T6358-25mg25mg£544.00
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TAR-T6358-50mg50mg£748.00
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TAR-T6358-100mg100mg£994.00
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TAR-T6358-500mg500mg£1,910.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
1-Azakenpaullone is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
CAS:
676596-65-9
Formula:
C15H10BrN3O
Molecular Weight:
328.169
Pathway:
PI3K/Akt/mTOR signaling; Stem Cells
Purity:
0.996
SMILES:
Brc1ccc2[nH]c-3c(CC(=O)Nc4cccnc-34)c2c1
Target:
GSK-3

References

Liu H, et al. Diabetes. 2009, 58(3), 663-672. Stukenbrock H, et al. J Med Chem. 2008, 51(7), 2196-2207. Kunick C, et al. Bioorg Med Chem Lett. 2004, 14(2), 413-416. Chan MH, et al. Schizophr Res. 2012, 136(1-3), 96-103. Mussmann R, et al. J Biol Chem. 2007, 282(16), 12030-12037.