CORM-3
Code | Size | Price |
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TAR-T6454-5mg | 5mg | £109.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6454-10mg | 10mg | £133.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6454-25mg | 25mg | £173.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6454-50mg | 50mg | £224.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6454-100mg | 100mg | £300.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity.
CAS:
475473-26-8
Formula:
C5H4ClNO5Ru
Molecular Weight:
294.61
Pathway:
Immunology/Inflammation; ; NF-κb
Purity:
0.98
SMILES:
[C-]#[O+].[C-]#[O+].[C-]#[O+].NCC(=O)O[Ru]Cl
Target:
NF-κB; NOD-like Receptor (NLR)
References
Tian X, Liu X, Wang A, et al. Bioluminescence Imaging of Carbon Monoxide in Living Cells and Nude Mice Based on Pd0-Mediated Tsuji?Trost Reaction. Analytical chemistry. 2018 May 1;90(9):5951-5958.
Ferr?ndiz ML, et al. Ann Rheum Dis. 2008 Sep;67(9):1211-7.
Huang Y, et al. Carbon monoxide (CO) inhibits hydrogen peroxide (H2O2)-induced oxidative stress and the activation of NF-?B signaling in lens epithelial cells. Exp Eye Res. 2018 Jan;166:29-39.
Long R, et al. Biochim Biophys Acta. 2014, 1837(1), 201-209.
Clark JE, et al. Circ Res. 2003, 93(2), e2-8.
Sawle P, et al. Br J Pharmacol. 2005, 145(6), 800-810.
Tian X, Liu X, Wang A, et al. Bioluminescence Imaging of Carbon Monoxide in Living Cells and Nude Mice Based on Pd0-Mediated Tsuji?Trost Reaction[J]. Analytical chemistry. 2018 May 1;90(9):5951-5958.