Glasdegib

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TargetMol
Product Code: TAR-T6514
Supplier: TargetMol
CodeSizePrice
TAR-T6514-1mg1mg£99.00
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TAR-T6514-5mg5mg£142.00
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Quantity:
TAR-T6514-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6514-10mg10mg£189.00
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TAR-T6514-25mg25mg£326.00
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TAR-T6514-50mg50mg£503.00
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TAR-T6514-100mg100mg£695.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2.
CAS:
1095173-27-5
Formula:
C21H22N6O
Molecular Weight:
374.448
Pathway:
Stem Cells; GPCR/G Protein
Purity:
0.98
SMILES:
CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N
Target:
Hedgehog/Smoothened; Smo

References

Munchhof MJ, et al. ACS Med Chem Lett. 2011, 3(2), 106-111.